The fate of any given contaminant in Amprenavir aquatic environment depends upon both its physicochemical properties, such as its solubility in water, Kow (octanol–water partitioning coefficient), Koc (organic carbon–water partitioning coefficient), etc., and other environmental characteristics, such as persistence, biodegradability, etc., which also influence the transport mechanisms among phases  and . Natural attenuation phenomena mainly include sorption on soils or sediments, sunlight photolysis, and other abiotic transformations (i.e. hydrolysis) . However, a significant persistence grade has been observed for IBP, for which also long-term biological degradation mechanisms appear to be scarcely active . Hence, the removal of IBP at its point of source, also including industrial effluents, is the most effective route for environmental protection. In Pacinian corpuscles framework, the ionization of the IBP molecule, as a function of the main thermodynamic parameters (pH, temperature, etc.), should be more accurately considered, as suggested by several researchers working in this field of investigation  and .